Innovation Kyoto 2021 Investment Limited Partnership ("KYOTO-ICAP No.2 Fund"), with Kyoto University Innovation Capital Corporation ("Kyoto iCAP") (Head Office: Sakyo-ku, Kyoto; Representative Director: Ko Kusumi) as unlimited liability partner, has made a new investment in Physiologus Technologies Inc. (Head office: Sagamihara City, Kanagawa Prefecture; Representative Director: Kazuyoshi Miyawaki), a developer of home dialysis equipment.

Overview of the investment
Dialysis is a treatment for patients with end-stage renal failure. 3 million people worldwide receive dialysis treatment, and the number of dialysis patients is increasing with the aging of society as a whole. Patients must go to a dialysis facility three times a week for four to five hours of treatment each time, creating a significant obstacle in their lives.

Although home dialysis at home is possible, it is not widely used at present due to the high hurdles to install the equipment. Existing home dialysis machines use more than 300 liters of purified water per dialysis session, which requires the installation of purified water production equipment and the payment of water expenses in addition to the dialysis machine, which are hurdles to introducing home dialysis. Physiologas has succeeded in developing a special column and has established a technology that can remove waste products from the patient's body without the use of purified water.

If the Physiologas dialysis machine is approved as a medical device and becomes available for general use, home dialysis will become more accessible, allowing patients to receive dialysis treatment at home at times convenient for them. In addition, it will be easier to increase the number of dialysis sessions and improve health conditions compared to facility dialysis.

Physiologus has recently signed a contract with the Advanced Medical Research and Development Organization of Kyoto University Hospital to provide support in clinical development and data analysis. Kyoto iCAP has decided to invest approximately 100 million yen in Physiologas' home dialysis machine, which is currently under development by Physiologas, in anticipation of its potential to bring significant benefits to dialysis patients, including improved quality of life.

Overview of Physiologas Technologies, Inc.
Establishment : March 2020
Business : Development of home dialysis equipment
Head Office: 1-15-1 Kitasato, Minami-ku, Sagamihara-shi, Kanagawa, Japan
Representative Director: Kazuyoshi Miyawaki
HP : https://physiologas.co.jp/

Kyoto University Innovation Capital, Co. Ltd.About
As a wholly-owned subsidiary of Kyoto University, Kyoto iCAP invests in and provides other business support to companies that utilize research results generated at Kyoto University and other national universities. The company currently operates the Innovation Kyoto 2016 Investment Limited Partnership ("KYOTO-iCAP No. 1 Fund") (established in January 2016) with a total value of 16 billion yen and the KYOTO-iCAP No. 2 Fund (established in January 2021) with a total value of 18.1 billion yen. The KYOTO-iCAP No. 1 Fund has a maturity of up to 20 years, and the KYOTO-iCAP No. 2 Fund has a maturity of up to 17 years, making it possible to provide long-term support for the practical application of research results from Kyoto University, which has strengths in basic research. The KYOTO-iCAP2 Fund has a maximum maturity of 17 years. In addition, a portion of the KYOTO-iCAP2 Fund will be invested in ventures originating from national universities other than Kyoto University.

Contact information for inquiries
Kyoto University Innovation Capital, Co. Ltd.
36-1, Yoshida Honmachi, Sakyo-ku, Kyoto 606-8317, Japan
Osami Kono, Senior Officer, Business Development Department
E-mail: info@kyoto-icap.co.jp
TEL: 075-753-7588